Summary of Puppy Mix

Projected Offspring Composition:

• 57.65% Poodle (Small and Standard combined)

• 25.4% Australian Shepherd

• 16.95% Bernese Mountain Dog

Pair Predictor Report for Buttercup & Rico’s Future Litter 🐾

At Stokeshire Designer Doodles, we carefully consider the genetic health and makeup of every potential pairing to ensure the healthiest, happiest puppies possible. Here’s what our genetic Pair Predictor reveals about the planned litter between:

• Sire: “Rico (Bruno)” — SDD Leonora's Rico of Phoenix

• Dam: “Buttercup” — SDD Moxie's Rohan Buttercup Stokes

🩺 Genetic Health Predictions

Our analysis shows that this pairing carries low genetic health risk, with most health concerns cleared for all puppies. Here’s the breakdown:

Clear for 14 Health Conditions
Including concerns often found in Australian Shepherds, Bernese Mountain Dogs, and Poodles — such as Degenerative Myelopathy, Von Willebrand Disease, Neonatal Encephalopathy, and many more. These puppies are predicted to be genetically free of these conditions.

Carrier Status

• Progressive Retinal Atrophy (prcd): There is a carrier risk for some puppies. Carriers are healthy themselves but should be considered in future breeding decisions.

At Risk

• MDR1 Drug Sensitivity: Some puppies may carry a risk for this gene, known to affect drug sensitivity, especially in Australian Shepherd heritage. We provide educational support for families to ensure safe care and medication plans.

Expected Coefficient of Inbreeding (eCOI)

• Expected eCOI for this litter: 3%

• Rico’s personal COI: 2%

• Buttercup’s personal COI: 0%

A low eCOI of 3% indicates minimal inbreeding, correlating with longer lifespans and improved overall health (Bannasch et al., 2021; Yordy et al., 2020).

Coat Colors & Composition

These puppies will likely feature a delightful blend of their parents’ breeds:

• 57.65% Poodle

• 25.4% Australian Shepherd

• 16.95% Bernese Mountain Dog

Expect beautiful coat variations, including wavy to curly textures in merle, tri, or phantom color patterns. These coats are typically low-shedding and hypoallergenic — perfect for families with mild allergies!

How to Use This Information

The Pair Predictor tool is just one part of our holistic approach to ethical breeding. We also assess:

• Temperament and behavior

• Conformation and structure

• Individual puppy testing

• Ideal family matches

For those exploring a puppy from this pairing, we’ll provide guidance on potential coat types, health testing, and early training to set your puppy up for success.

Curious how these traits and genetic insights align with your family’s needs?
Let’s chat about your goals and how a puppy from Buttercup and Rico’s litter could be a perfect fit.

MDR1 Drug Sensitivity

What is MDR1?
MDR1 (Multi-Drug Resistance 1) is a gene that produces a protein essential for removing certain drugs from the brain and bloodstream. When a dog carries a mutation in this gene, their ability to process and eliminate certain medications is impaired.

Why it Matters:
Dogs with MDR1 mutations are at increased risk of severe or even life-threatening reactions to specific drugs, including common medications like ivermectin (heartworm preventatives), loperamide (Imodium), and some chemotherapy drugs.

For Our Puppies:
In the pairing of Buttercup and Rico, there’s a possibility that some puppies could inherit the MDR1 mutation from the Australian Shepherd line. This doesn’t affect their daily health or happiness — but it’s crucial to inform your veterinarian about MDR1 sensitivity if your puppy tests positive. Adjusting medications and doses can keep your dog safe and healthy for life.

Our Commitment:
We offer comprehensive genetic testing for puppies before they join their new families, so you’ll know whether MDR1 precautions are needed. We’re always here to answer questions and help you work with your vet to create a safe, tailored healthcare plan.